Having a high FOC (Forward Of Center) weight, will improve penetration.
There's more that goes into having the higher FOC, like having a stiff enough spine arrow shaft to support having that weight forward. I find it easier to get the bow in tune with a heavy arrow setup, than a light arrow setup. Plus, the bow is quieter and the heavier arrows have more stable arrow flight.
My Elite HNTR33 has a 58# DW at a 29" DL. It shoots a 27.25" Gold Tip Kinetic 300 spine (10.4 gpi) with a 25 gr. insert, 100 gr. tip weight and 50 gr. of internal shaft weight and 2.75" vanes. This produces 175 grains at a 12% FOC and a TAW (Total Arrow Weight) of 490 grains.
My Elite Ritual 30 has a 57# DW at a 29" DL. It shoots a 27" Gold Tip HunterXT 300 spine (9.3 gpi) with a 100 gr. brass insert, 150 gr. tip weight and 3" feathers. This produces 250 grains at a 22% FOC and a TAW of 525 grains.
Both of these bows are sighted in to 50 yards, have perfect arrow flight with a bare shaft at 20 yards and are very quiet upon release.

I like pass-thru shots! Two holes bleeding are better than one. The percentages of finding a deer are 72% higher with a pass-thru shot, so says the United Blood Trackers group that uses dogs for deer recovery.