If I lost you on the T/C rifles... the T/C Contender is a single-shot break-action frame with interchangeable barrels. It was originally developed for metallic silhouette handgun competition; as such it will take (most) non-magnum centerfire cartridges. The Encore is a later, stronger, upgraded version that will take magnum cartridges. Encore barrels won't fit on a Contender frame and vice-versa. Both will take shotgun and muzzleloader barrels. T/C also makes excellent muzzleloader rifles, both sidelock and in-line. So, with one "firearm" (ie, the receiver with the serial number) you can buy as many barrels as you have the budget or storage space for. The scope mounts to the barrel, instead of the receiver, so you can swap out barrels with zero-to-almost-zero change in point-of-impact. These guns are especially attractive to people who like to tinker, or experiment with new and interesting cartridges, including "wildcat" cartridges, people who don't want to own that many guns (maybe because their state is hostile to gun owners), people with limited storage space, people who hunt in different jurisdictions with different caliber restrictions or requirements, etc.
Tinkering handloaders especially gravitate to these guns because the barrels are so readily available. Your gunsmith (or you, if you have the tools and inclination) can get a barrel and cut whatever chambers you want. Say you had a 300BLK barrel, and you decided you didn't like it anymore, or maybe you shot it so much the throat has eroded and accuracy is now suffering. You could ream it out to .30 Herrett, or .30-30, or .308, or .30-06, or (with an Encore) 300 Win Mag, or any of the Ackley Improved versions of the above. With a .38SPL barrel, you could go to 357 Mag or 37 Maximum, or 360 Buckhammer, or .35 Whelan AI, or 358 Winchester, or .357 Herrett, etc., etc. Since it's a single shot you'll never have to worry about magazines or feeding or opening up a bolt face, or taking an entire rifle out of commission while it's at the gunsmith trying to sort out feeding issues or whatever. If you don't like it, you can put the barrel on an auction site and replace it without dealing with a gun shop or filling out ATF paperwork. T/C barrels are available from T/C, Bergara, Match Grade Machine, and other places. There's even a gunsmith (Bellm T/Cs) specializing in these rifles, with his own aftermarket parts and accessories.
With one gun and a handful of barrels, you're set for small game with a .22 or .17, upland game with a 20ga barrel, southern MN with a rifled slug barrel, Indiana with a straight-wall (.45-70, .444, 350LEGEND, etc.) barrel, Western elk with a 7mmRM or 300WinMag, muzzleloader deer, varmints with a .220 Swift or .223 or .22Hornet, etc. You'd still need a flintlock for late PA season, and a big-bore repeater for grizzly country, but otherwise you're set for the vast majority of North America with 1 gun - which, incidentally, doesn't have any of the scary features that might get you in trouble if your plane lands in IL or NJ or someplace similar.