This is gonna probably start some controversy but I'll share it anyway...
Now if we are strictly talking firearms, my aim point is center of the neck a couple of inches in front of the shoulder if I have a good angle and clear shot. If not, then the tried and true on the shoulder, just behind the shoulder or center of chest (if head on).
Years ago I watched a TV celebrity hunter and his wife take this shot at 160yds with a muzzle loader and the buck dropped right there. I must have replayed the video a dozen times to verify what I saw and sure enough the bullet impact was on the neck. No, they never mentioned where the bullet hit or even hinted on the aim point but it damn well showed up in the video.
So that year during the firearms season I shot a doe with a 12ga at 65yds the same way, in front of the shoulder on the neck and she dropped right there. Right there meaning in her tracks literally, not one step, no movement except her dropping straight to the ground. Ever since that time when the shot presented itself I took it, the closest being 20yds and the furthest at 82yds and every time it had the same effect, a dead doe laying in the last spot she stood. I like this shot also for the fact that it doesn't destroy the front shoulder and ruin the meat in the area.
As far as with a bow, with the videos posted in this chat I myself have changed my aim point slightly further back than the "vital vee" for a few reasons.
Most importantly it gives me more room to MISS the shoulder/ leg bone should I screw up the shot, deer moves, Mr. Murphy shows up etc. Ideally we all want a double lung shot with a piece of the heart for a quick clean ethical kill but know that sometimes it's not that easy or doesn't wind up that way. I consider any combination of lung/heart, lung/liver, liver and/or stomach to be lethal shots, what changes is how I proceed with the recovery. So altering my aim a tad rearward gives me a larger "kill" area.
What I think is lost in most discussions is the fact that from a shear killing point of view, an arrow mid-line or lower between the front shoulders and rear hams ends with a dead deer. Now yes there will be rare instances that the broad head misses everything vital on the inside and the animal lives. Whether a hunter can successfully recover a liver/stomach hit animal is another matter and this is where I find most discussions related to lethal hits to become obscure because these are two distinctly separate issues which get bundled together . One is a "bad shot" to the liver or gut (which is lethal) and the other is the challenges it presents due to little or no blood trail and mandatory wait time before beginning the tracking/recovery phase. But a liver or gut shot is a death sentence for a deer, the difference being the length of time it takes for it to expire.