Depends. With a 6.5 you can make that shot with almost any barrel, would a competition barrel make it easier? Of course, is it worth the extra money, well that up to you. But for that application idk what your pronghorn opportunity is like but I would just rent a rifle for a hunt like that. That way I wouldnot spend all this money building 6.5 Grendel and only use it once a year to snipe a pronghorn. Which by the way you can do with a good ol’ .308 or 338 Lapua. Idk where this push for these huge rounds came from but unless your a sniper or have a dying passion to shoot long distance 6.5 is overkill for most.